03/04/2013 0 Comments

Doctors from the University of Florida College of Medicine performed a review of records of all patients at their institution who underwent both a glaucoma drainage device placement and penetrating keratoplasty from January 1, 1998 to December 31, 2003, and determined that GDD placement can provide glaucoma control in a high percentage (71 percent) of eyes with PK, even at five years. Glaucoma outcome was assessed by postoperative intraocular pressure, number of glaucoma medications and need for further glaucoma surgery, while corneal grafts were assessed for clarity.

Twenty-eight eyes of 27 patients were studied. All eyes had GDD placement in the anterior chamber. The mean pre-GDD IOP was 28.8 ±10.3 mmHg on a mean of 2.6 ±0.8 glaucoma medications. At five-year follow-up, the mean IOP was 13.0 ±5.9 mmHg on a mean of 0.9 ±1.0 medications. GDD implantation successfully controlled glaucoma in 96 percent at one year, 86 at two years, 79 at three, 75 at four and 71 percent at five years. Grafts remained clear in 96 percent at one year, 82 at two years, 75 at three, 57 at four and 54 percent at five years. The success of PK in GGD remains reasonable (54 percent) at five years. IOP control and graft survival rates are comparable with earlier published studies with shorter follow-up or tube placement in the vitreous cavity. Failure of glaucoma outcome or graft survival was associated with prior intraocular surgeries.
J Glaucoma 2012;21:608-614
Knape R, Szymarek T, Tuli S, Driebe W, et al.

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